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Two glitches may be referred to as Substitute glitch.
- Selfdestruct and Substitute glitch, a battle glitch that allows the user of Selfdestruct / Explosion not to faint against a Substitute
- Confusion and Substitute glitch, a battle glitch in which damage is dealt to the opponent Pokémon's Substitute instead of the user's when a Pokémon under a Substitute is hurt from its confusion.